scloop

Guides

Task-focused sections grouped by pipeline stage.

Preprocessing

Prepare AnnData

Downsample cells and build the embedding.

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Feature selection

Select variable genes.

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Finding loops

Find loops

Detect loops and test them on bootstrap samples.

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Bootstrap settings

Sample count, sampling method, presence test.

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Analyzing loops

Trajectories and gene trends

Fit paths around a loop and smooth gene expression along them.

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Hodge decomposition

Embed loop edges with the Hodge Laplacian.

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Plotting

Persistence diagrams, loop landscapes, loop rank.

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Matching and I/O

Match loops

Match loops between datasets.

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Save and load

Write and read scloop results with h5ad.

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